[Updated 12/1/2020]Moderna (NASDAQ Arcturus in a statement on Tuesday said that this first phase of the trial … SINGAPORE has made arrangements with various pharmaceutical companies to facilitate their clinical trials and drug development in Singapore, with the government having attracted a few players to establish vaccine manufacturing capabilities here.  There could be challenges in areas such as Immuno-Oncology as well, where Moderna is betting big. The US pharmaceutical company and its German partner announced earlier last month that final results from its vaccine trial showed that it is 95 per cent effective . China's capabilities mean it could produce vaccines developed by other countries as well. The platform uses extensive data to show in a single snapshot what drives the value of a company's business. Once the vaccine is produced, the fill-finish operation – which is the process of filling vials and packaging the vaccine for distribution – is handled by Catalent The theme is up by about 721 % year-to-date versus about 13% for the S&P 500. NDAQ Australia expects to start administering the first dose in mid-to-late February to priority groups, including quarantine and border workers, frontline healthcare workers, and residents in aged and disability care. The company could supply about 40 million doses in the United States in 2020 if the data is positive and regulators approve the vaccine. This is an important addition to the manufacturing capacity needed by global pharmaceutical and vaccine companies in the ongoing fight against COVID-19. Following are all of the companies that are actively developing COVID-19 vaccines either on their own or in partnership with another drugmaker. Here's what we know about Covid-19 vaccines in Asia Pacific. A health official prepares a vaccine kit during a Covid-19 vaccine mock drill in Chennai on January 2. AstraZeneca’s vaccine, on the other hand, faces concerns regarding some gaps in its trial data, which could undermine its reported results. Moderna indicates that it could have about 20 million doses of its vaccine ready by this year and expects to produce between 500 million to 1 billion doses next year in collaboration with Switzerland-based Lonza. The theme is up by about 877% year-to-date versus about 14% for the S&P 500. The vaccine will be free of charge, with a goal to vaccinate 50 million people ahead of February's Lunar New Year celebrations. On Thursday, December 24, 2020, in Dublin, Ireland. This is positive news, considering that Moderna has no real manufacturing track record and has never produced or sold a commercial drug prior to the Covid-19 shot. Japan ranks "among the countries with the lowest vaccine confidence in the world," according to a recent study by The Lancet. No estimate was given for Novavax. Other areas? The company has received about $1.6 billion in funding from the Federal government. India, second only to the US in the number of coronavirus cases worldwide. Combined with the large public interest in facilitating vaccine access, these margins may face even more downward pressure. The stock is down by -5.1% this year. The vial filling and packaging will be handled by Catalent, a contract manufacturing company. The theme is up by about 640% year-to-date versus about 13% for the S&P 500. Not so fast: analysts, After Admitting Mistake, AstraZeneca Faces Difficult Questions About Its Vaccine. On top of this, vaccine manufacturers are required to … . By the end of March, four million people should have been vaccinated, according to Prime Minister Scott Morrison. Pfizer’s vaccine could also face logistical issues, considering that the vaccine needs to be stored at a temperature of minus 94 degrees Fahrenheit. If Moderna’s success is for some reason limited to certain infectious disease vaccines, its long term outlook might not be as promising, given the lower margins that vaccines typically command. The country is still evaluating other candidates, including China's. Surprisingly, the founders of Trefis discovered that along with most other people they just did not understand even the seemingly familiar companies around them: Apple, Google, Coca Cola, Walmart, GE, Ford, Gap, and others. This is also the age range recommended by most of the manufacturers and for which the vaccines are approved for use in Singapore by the Health Sciences Authority. Once the genetic code of a virus is available, Moderna essentially adapts messenger RNA to trigger the immune system to produce protective antibodies without using the actual part of the virus, unlike traditional vaccines. SINGAPORE - When asked if they would take the Covid-19 jab once it hits the market, some well-known Singaporeans had mixed views. He added that they are working to move up the Pfizer vaccine, to potentially the second quarter. mRNA offers significant flexibility with vaccine and potentially drug development. The stock is up 253% this year. So how is the company going to meet demand? in the U.S., and by ROVI and Recipharm outside the U.S. See our indicative theme of Covid-19 Vaccine stocks which includes U.S.-listed pharma and biotech companies. Currently, there is only one type of Covid-19 vaccine available in Singapore. An illustrative photo showing medical syringes seen in front of Moderna logo displayed on screens in ... [+] the background on Christmas Eve. STRONG MANUFACTURING PRESENCE IN SINGAPORE. Singapore is in talks with major suppliers of COVID-19 vaccines on the possibility of being a regional distributor and playing a part in the final stages of vaccine production, Trade and Industry Minister Chan Chun Sing said on Monday. Novavax (NVAX), a vaccine development company, began late-stage trials of its Covid vaccine in the U.K in September, and large-scale phase 3 trials are due to begin in the U.S. and Mexico this month. (Photo illustration by Artur Widak/NurPhoto via Getty Images), EY & Citi On The Importance Of Resilience And Innovation, Impact 50: Investors Seeking Profit — And Pushing For Change. Two shots of the vaccine will be required per person. See our indicative theme of Covid-19 Vaccine stocks – which includes U.S.-listed pharma and biotech companies. While Moderna’s stock trades at about $150 per share, its valuation still looks reasonable at about 25x our projected 2020 EPS. The company has 21 programs underway, around 13 of which are in the clinical stage. SINGAPORE - The Republic is building up its vaccine-manufacturing capacity even as researchers around the world race to develop one for Covid … Singapore is building up its vaccine manufacturing capacity in order to offer fill and finish contract manufacturing services to vaccine developers, Singapore Prime … Arcturus Therapeutics announced on Dec. 28 that it received approval from the Singapore Health Sciences Authority to proceed with a Phase 2 clinical study of its vaccine candidate ARCT-021, also known as LUNAR-COV19. (CNN)One year after the Covid-19 outbreak began, countries around the world are racing to secure and distribute vaccines to their citizens. Pfizer’s vaccine is about 95% effective based on phase 3 data, but it needs to be stored at extremely cold temperatures of minus 94 degrees Fahrenheit, calling for specialized freezers. While the company doesn’t have any other products on the market yet, its flu vaccine NanoFlu could be ready for potential FDA approval. the background on Christmas Eve. © 2021 Forbes Media LLC. The companies are on track to file an emergency use application with the U.S. FDA later this month if pending data indicates that the vaccine is safe. As well as global, regional and local commercial operations, we have a significant manufacturing presence in Singapore, comprising two global manufacturing supply sites and a vaccines manufacturing facility. Is this jump warranted? Elderly citizens, health care workers, and those with chronic illness will be first in line to receive a free dose when the initial batch of a million Sinovac doses arrives in January. See their vaccine plan, China's Sinopharm says its Covid-19 vaccine is 79% effective, China approves Sinopharm Covid-19 vaccine, promises free shots for all citizens, New Zealand commits to travel bubbles with Australia, Cook Islands. (related: A Look At Moderna’s Pipeline Beyond The Covid Vaccine). Most other countries are still waiting on local regulators to approve vaccine candidates before they can roll out inoculation programs -- and in the meantime, are scrambling to sign deals with pharmaceutical companies to buy the coveted doses in advance. As we’ve said before, Moderna’s Covid-19 vaccine is likely to emerge as the most sought-after vaccine in developed markets, considering its stellar efficacy rates and relative ease of storage. Country has 2nd highest Covid-19 cases. The company is likely to have efficacy data from late-stage trials available shortly. Investors cheered the news, sending Moderna stock up by about 20% on Monday’s trading. Chinese Premier Li Keqiang said some Southeast Asian countries would be given priority, including Cambodia, Laos, Myanmar, Thailand and Vietnam. India has authorized two Covid-19 vaccines for use, putting its enormous vaccine-manufacturing capacity in the spotlight. See all Trefis Price Estimates and Download Trefis Data here, What’s behind Trefis? In Asia, only a handful of countries have reached this stage -- the biggest being China and India, which have the extensive manufacturing capabilities necessary to serve as regional vaccine production hubs. The Pfizer-BioNTech vaccine arrived at Changi Airport aboard a scheduled SIA Boeing 747-400 freighter service from the Belgian capital Brussels at about 7.35pm. Gan added that vaccine recipients will also be observed on-site for 30 minutes after receiving their vaccination, so that any severe allergic reactions such as anaphylaxis can be detected and promptly treated. Prime Minister Jacinda Ardern has said upon approval, the first batches will be delivered to frontline workers and essential staff by the second quarter of 2021. The Vaccine Business Unit based in Singapore hosts a laboratory for analytics and development of vaccines to protect against important infectious diseases in the region. What if you’re looking for a more balanced portfolio instead? Overall, Moderna’s vaccine could offer the best of both worlds – high effectiveness and easier logistics, although it could be slightly more difficult to manufacture compared to Pfizer’s. Moderna’s vaccine will also be more expensive than rivals, as it is likely to cost between $25 and $37 per dose, depending on the volume of the order, compared to about $19 per dose for the Pzifer vaccine. See our indicative theme of Covid-19 Vaccine stocks – which includes U.S.-listed pharma and biotech companies. Once a large percentage of the global population is vaccinated (likely by 2022 or 2023) the earnings potential of the Covid vaccine will diminish. Being a clinical-stage biotech, Moderna also lacks the sophisticated supply chain of big pharma companies such as Pfizer and Johnson & Johnson. The country will also secure enough vaccines to cover Pacific Islands including Samoa, Tuvalu, Tokelau, Niue, and the Cook Islands, according to CNN affiliate, Australia's Pfizer doses will be manufactured in the US and Europe, the Oxford-AstraZeneca vaccine will be. — Bernama pic. ), More importantly for Moderna investors, the vaccine’s results also bode well for the rest of the company’s pipeline, which is entirely based on mRNA technology which has never been used previously in commercial drugs. Can Senate Handle Trump’s Impeachment And A New Stimulus Package At Once? Japan has not yet approved any vaccine, and has faced criticism over its slowness to act as cases reach new daily highs, prompting leaders to declare a state of emergency for the capital Tokyo in January. high-quality portfolio to beat the market, Lonza gets Swiss OK to start Moderna vaccine production -paper, How mRNA vaccines from Pfizer and Moderna work, Moderna’s Covid-19 vaccine was designed in just two days, Pfizer-BioNTech COVID-19 vaccine data ‘open the floodgates’ for mRNA in infectious disease. [Updated 11/4/2020] Covid-19 Vaccine stocks. Now the initial data from Pfizer and its German partner BioNtech’s Covid-19 vaccine appears to confirm this, with the vaccine’s efficacy standing at 90% based on initial data, versus the U.S. FDA’s baseline efficacy requirement of just 50% for the approval for Covid-19 vaccines. The stock has more than doubled over the last month as the company began publishing efficacy data. NSA Will Install Trump Loyalist Michael Ellis As Its General Counsel, Stocks This Week: Sell Short General Dynamics And Transocean, Fauci Warns Of ‘Ominous’ New Covid-19 Strains, Says Biden Can Achieve Aggressive Goal Of Vaccinating 100 Million In 100 Days, January’s Message: 2021 Is Not 2020. The company also said that it was continuing to invest and add staff to potentially produce as much as 1 billion doses for the full year. You can play with assumptions, or try scenarios, as-well-as ask questions to other users and experts. Separately, Swiss regulators have reportedly allowed Moderna’s contract manufacturer Lonza Group to start producing its Covid-19 vaccine at a plant in Switzerland, which will apparently have a capacity to produce 800,000 doses a day. The Pfizer-BioNTech vaccine is expected to approved by Australian regulators by the end of January, Morrison said. SINGAPORE, Dec 21 — Singapore received its first shipment of Covid-19 vaccine this evening on board a Singapore Airlines (SIA) cargo flight from Belgium, where it was manufactured. Moderna’s Covid-19 vaccine could emerge as the most sought-after vaccine, particularly in developed markets – considering the high levels of efficacy as well as manageable refrigeration requirements, unlike Pfizer’s candidate which is also highly effective but needs to be stored at ultra-cold temperatures. The vaccination card will indicate the vaccine that was administered and the date for the second vaccine dose. Chan, however, did not … Large parts of the rich … MSD manufactures medicines and vaccines that are sold in more than 140 countries. The stock has soared 2,000% year-to-date. With enough doses secured for 44 million people, the government is aiming to vaccinate 80% of its population. Singapore: The first batch of volunteers aged between 21 and 55 in Singapore have received a dose of a potential coronavirus vaccine being developed in the country. For instance, the company Shenzhen Kangtai Biological Products has already. mRNA-based Covid vaccines focused on the novel coronavirus’ spike protein – which is on the outside of the virus – but there are other viruses whose harmful regions are hidden, making it more difficult for mRNA to address. Here’s Why, China’s Rare Earths ‘Slump’ A Sign Of Domestic ‘Hoarding’ For EV Batteries, And More, The Flawed Inflation Narrative; And “V” vs. “U”, It’s Been A Numbers Game For Netflix And Investors Want To See How They All Added Up. The vaccine is likely to be priced at between $25 to $37 per dose, with two doses required per person. Switzerland-based Lonza, one of the world’s largest pharmaceutical services companies, will produce the key mRNA active ingredient for the vaccine in New Hampshire and Switzerland. Arcturus (Nasdaq: ARCT) hopes the compound will prove effective as a vaccine against SARS-CoV-2, the virus that causes COVID-19. How Will The Covid-19 Vaccine Impact Moderna’s EPS? Data sources: Biotechnology Innovation Organizati… Some countries like the United States and United Kingdom have already begun vaccinating priority groups and the public. Sanofi is another of the top vaccine manufacturers in the world specialized in research and … While Moderna has a Covid vaccine of its own in the works, with efficacy data expected any time now, the strong response of Pfizer’s mRNA bodes well not just for Moderna’s Covid efforts, but also for the rest of the company’s sizable pipeline which is focused mostly on vaccines and therapies for rare diseases. Here’s a high-quality portfolio to beat the market, with about 120% return since 2016, versus about 60% for the S&P 500. That’s below the S&P 500 that trades at about 26x projected earnings. KUALA LUMPUR, Dec 28 — Pharmaniaga Bhd is ready to efficiently distribute Covid-19 vaccines which are expected to be ready by the first quarter of 2021, as soon as it receives the go-ahead from the government. Our indicative theme of Covid-19 Vaccine stocks – which includes a diverse set of U.S.-based pharma and biotech companies developing Covid vaccines – is up by about 560% year-to-date, on an equally weighted basis, compared to the S&P 500 which has gained just about 4% over the same period. , Moderna is working with multiple partners to produce its vaccine. Novartis provides healthcare solutions that improve and extend people’s lives. Called Lunar-Cov19, the vaccine is developed by Duke-NUS Medical School and American pharmaceutical company Arcturus Therapeutics. (related: How Will The Covid-19 Vaccine Impact Moderna’s EPS?) With ongoing trials in more than a dozen countries, China will be sending out hundreds of millions of doses in the coming months. 6. Although the number could change as more data comes in, it is nevertheless indicative of a highly effective vaccine. In fact, we think that the strong data from the vaccine – which is developed using messenger RNA (mRNA) technology could actually mean a lot more for Moderna (NASDAQ: MRNA), another Covid-19 vaccine player, whose entire drug pipeline is based on mRNA technology. Updated 0231 GMT (1031 HKT) January 9, 2021. Other major vaccine makers including Oxford-AstraZeneca, Moderna, and Novavax have also signed deals to provide Japan hundreds of millions of doses in total. But the emergency-use approval comes with restrictions on global distribution. The country is also working to secure deals with American companies. A coolroom at Singapore's Changi Airport, preparing for the arrival of its first shipment of Pfizer-BioNTech vaccines, on December 16, 2020. (related: How Will The Covid-19 Vaccine Impact Moderna’s EPS? See our indicative theme of Covid-19 Vaccine stocks – which includes U.S.-listed pharma and biotech companies. The central government will cover the cost, allowing residents to receive the vaccine. We think it largely is, but there are some risks as well. [11/27/2020] What’s Happening With Moderna Stock?Moderna (NASDAQ: MRNA) stock rallied by over 10% on Wednesday’s trading after the European Union agreed to buy 80 million doses of its Covid-19 vaccine, with an option to buy up an additional 80 million doses. You may opt-out by. However, there are a couple of factors that could help the company scale up quickly. Using a lower-dose first shot, which conserves the vaccine, and then a full-dose second shot provided protection about 90% of the time, the company and university found. CTLT Considering that the vaccine is co-developed with BioNTech, any profits will likely be shared. Janssen vaccinations could start in the second quarter, and Pfizer vaccines will arrive in the third quarter, according to Prime Minister Chung Sye-kyun. Read more at The Business Times. SII is allowed to produce the Oxford-AstraZeneca vaccine for use within India, but the government has barred them for export until at least March or April -- meaning other countries may have to source their Oxford-AstraZeneca doses from other production sites. [Updated 11/11/2020] Why Pfizer’s Vaccine Data Is Good News For Moderna. Moreover, the mRNA technology that Moderna (and Pfizer) are using requires specialized manufacturing equipment. novartis singapore pharmaceutical manufacturing Novartis was created in 1996 through the merger of Ciba-Geigy and Sandoz and has a rich history spanning over 200 years. Both vaccines will be administered in two doses. Comprised of companies with strong revenue growth, healthy profits, lots of cash, and low risk, it has outperformed the broader market year after year, consistently. For perspective, Pfizer has agreed to supply the U.S. government with the vaccine at about $19.50 per dose, and it’s possible that average prices could be well below this, considering that pricing might be lower in emerging markets. For instance, even Pfizer, which also uses mRNA technology and has an established manufacturing base, had to halve its initial vaccine production target for this year to 50 million doses due to some supply chain constraints. There is a lot of competition in the race for a Covid-19 vaccine, and it’s likely that there will be multiple successful candidates from other companies. • In Singapore, the Expert Committee on Immunisation (ECI) recommends the HPV vaccination for females aged nine to 26 years old. Most countries in Southeast Asia have not approved vaccines yet -- but nearly all have signed deals to receive China's vaccine candidates, as well as signing additional deals with other providers. The company already has supply agreements with the U.S., Canada, Japan, the U.K., Israel, Qatar, and Switzerland and is also having discussions with several other countries. This could potentially limit the use of Pfizer’s vaccine to clinics and hospitals that have the appropriate storage facilities. While Moderna intends to produce between 500 million to 1 billion doses of its vaccine over 2021, it has no real manufacturing track record and has never produced or sold a commercial drug to date. On Thursday, December 24, 2020, in Dublin, Ireland.  However, it should be noted that sales of the vaccine will be significantly front-loaded. (related: How Will The Covid-19 Vaccine Impact Moderna’s EPS?) The Oxford-AstraZeneca vaccine could be approved in February. [Updated 11/10/2020] What Does Pfizer’s Vaccine Readout Mean For Its Stock?Pfizer (NYSE: PFE) and its German partner BioNTech indicated that their Coronavirus vaccine, dubbed BNT162b2, was over 90% effective at preventing Covid-19 infections among volunteers, based on early data from phase 3 trials. Sanofi. While Pfizer‘s (NYSE: PFE) surprisingly strong initial Covid-19 vaccine efficacy readout likely marks the beginning of the end of the Covid-19 pandemic, it probably doesn’t mean too much for Pfizer stock, given the limited potential profits and challenges with distribution. Unlike traditional vaccines which use a virus protein that needs to be grown over the course of weeks, mRNA molecules – which instruct the body to produce virus proteins by itself – are less complex and are produced via a chemical process (rather than a biological process) making mass production much quicker. Chinese leaders have promised a growing list of developing countries priority access to its successful vaccines. Also, vaccines traditionally have lower profitability versus prescription drugs. The theme is up by about 540% year-to-date versus about 10% for the S&P 500. Aside from the approved Sinopharm vaccine, China has four vaccine candidates which have reached Phase 3 trials. Moderna (MRNA) , a clinical-stage biotech company, is carrying out phase 3 trials of its Covid-19 vaccine, completing enrollment of 30,000 participants. Led by MIT engineers and Wall Street analysts, Trefis (through its dashboards platform dashboards.trefis.com) helps you understand how a company's products, that you touch, read, or hear about everyday, impact its stock price. Mr Gan said Singapore is expecting more Covid-19 vaccine deliveries in the next few months, including from US biotechnology firm Moderna and China's Sinovac. The government agency has invested $45 million to support the manufacturing process of ARCT-021 vaccine. Japanese Prime Minister Yoshihide Suga at a press conference in Tokyo on January 4. The vaccine will also be the first to seek emergency use approval from the FDA. That being said, some hiccups are to be expected as the company works with a tight timeline. Moderna’s Cytomegalovirus (CMV) vaccine, which is currently in phase 2 studies and could move to phase 3 in 2021, is likely to be the company’s first candidate for approval after its Covid-19 vaccine.  The companies … Moderna (NASDAQ: MRNA) provided updates on the manufacturing of its Covid-19 vaccine, noting that it was increasing the baseline production estimate for this year to 600 million doses, 100 million more than it had initially projected. Both governments have said the vaccines will be free and voluntary for citizens. We estimate that the vaccine will add roughly $6 to Moderna’s EPS each year over 2021 and 2022. Trefis is currently used by hundreds of thousands of investors, company employees, and business professionals. While Pfizer stock was up by almost 8% following the news, we think it’s unlikely that the vaccine will meaningfully move the needle for the company for multiple reasons. While there are two other vaccines by drug majors Pfizer and AstraZeneca that have reported phase 3 results, it looks like Moderna’s vaccine offers the best balance of efficacy and ease of storage and distribution. Some risks as well as regional export center that sales of the rich … Updated 0231 GMT 1031! Well as regional vaccine manufacturing companies in singapore center change as more data comes in, it nevertheless., a contract manufacturing company facilitating vaccine access, these margins may even. Emergency use approval from the FDA company has received about $ 1.6 billion in funding from Federal! 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